Mesothelioma – Risk Factors And Symptoms

Mesothelioma, an elusive and aggressive malignancy, predominantly targets the protective lining of vital organs such as the lungs, heart, and abdomen. While this form of cancer may not be known, its strong association with asbestos exposure has thrust it into the limelight in medical and legal discussions. A thorough understanding of its risk factors and symptoms is crucial, not only for those directly affected but also for society as a whole. Early detection can drastically increase the odds of a favorable prognosis.

In this article, we aim to discuss the complexities of mesothelioma, equipping readers with vital knowledge that could be pivotal to their well-being.

Risk Factors

A risk factor is a feature, characteristic, or exposure that enhances the likelihood of developing a disease or injury. Risk factors can be classed as either modifiable or non-modifiable. Modifiable risk factors like diet or drinking habits can be changed or controlled. In contrast, non-modifiable factors like age or family history cannot be altered. Several risk factors have been pinpointed regarding mesothelioma, with asbestos exposure being the most significant.

If you or a loved one has been subjected to asbestos exposure due to the negligence of a third party, considering legal recourse is advised. For this purpose, approaching reliable law firms like Sokolove Law will prove worthwhile. They possess the knowledge and expertise to navigate complex mesothelioma cases and can assist you in filing a lawsuit.

Now, let’s discuss the risk factors:

Asbestos: Asbestos, in the simplest terms, is a naturally occurring fibrous mineral. It was widely utilized in different sectors due to its resistance to heat, electricity, and corrosion. When asbestos fibers in the air are inhaled, they travel through the blood and embed in the lungs. Over time, these fibers can irritate and inflame the pleural cells, potentially leading to genetic mutations that culminate in mesothelioma. There are several contexts where the risk of asbestos exposure is elevated:

  • Occupational exposure: Individuals employed in certain industries, such as shipbuilding, mining, insulation, and construction, faced heightened risks of encountering asbestos. And this was particularly true before regulations were revised in the 1980s.
  • Secondary exposure: Even if one is not directly in contact with asbestos, the risk of exposure remains through secondary means. This variant of exposure frequently arises when asbestos workers carry asbestos fibers into their homes on their clothing, hair, or tools, subsequently exposing their family members.
  • Environmental exposure: Residing close to natural asbestos deposits or in proximity to industries utilizing asbestos in their operations can inadvertently expose residents to this carcinogenic material.
  1. Age

The likelihood of acquiring mesothelioma rises with age since mesothelioma normally takes 20-60 years to develop after exposure. Yet this does not mean young people do not develop mesothelioma from asbestos exposure. Cases have been seen in teens and adults under 45, but it is rare.

  1. Gender

Mesothelioma is far more common in men than in women. This gap is mostly due to occupational exposure, as many industries with heavy asbestos previously hired men mostly. On the other hand, women are likelier to develop mesothelioma through secondary exposure or asbestos exposure through contaminated talc used in talc powder.

  1. Genetics

Some people may possess a genetic makeup (mutation or change in gene BAP1) that makes them more prone to developing mesothelioma after asbestos exposure. It could be due to their body’s inability to repair DNA damage induced by asbestos fibers or other hereditary factors that accelerate cancer growth.


Mesothelioma can manifest in various forms, each with its distinct symptoms. Yet, some symptoms are common across all subtypes, while others are specific to the location of the cancers. The symptoms can run from mild to severe and even become more pronounced as the disease progresses. Hence, those at risk must identify these signs for timely intervention.

Common Symptoms Across All Subtypes

  • Fatigue: A pervasive tiredness that does not improve with rest is commonly reported.
  • Unexplained weight loss: The body’s increased metabolic demand or reduced appetite.
  • Pain: Depending on the site of the tumor, pain can manifest in the chest or abdomen.
  • Lumps of tissues.

Symptoms by Mesothelioma Subtypes

  1. Pleural Mesothelioma

A subtype of mesothelioma that mainly affects the thin membrane covering the lungs. Symptoms include:

  • Shortness of breath
  • Persistent cough – mainly dry
  • Chest pain or tightness
  1. Peritoneal Mesothelioma (Abdomen)

This type affects the lining of the abdominal cavity. Apart from the common symptoms, patients with peritoneal mesothelioma might also experience:

  • Abdominal Swelling or Pain: Accumulation of fluid or tumor maturing in the abdomen can lead to swelling and discomfort.
  • Nausea or Vomiting: As the tumor presses on the stomach or intestines, it can interfere with digestion leading to nausea or vomiting.
  • Constipation or Diarrhea: The tumor can press against or invade the intestines, causing changes in bowel movements.
  1. Pericardial Mesothelioma (Heart)

Affecting the lining around the heart, pericardial mesothelioma’s distinct symptoms are:

  • Chest Pain: This is directly associated with the heart’s proximity.
  • Irregular Heartbeat: Also termed arrhythmias, tumor growth can interfere with the heart’s normal rhythm. These can range from benign palpitations to life-threatening conditions.
  • Shortness of Breath: Fluid buildup around the heart (pericardial effusion) can restrict its movement, leading to breathlessness.
  1. Testicular Mesothelioma

Though rare, this subtype affects the lining around the testicles, leading to:

  • Swelling or Lumps in the Testicles: The most indicative symptom, often felt as a mass.
  • Pain in the Testes: Ranging from mild to severe, depending on tumor size and location.

Because the symptoms of mesothelioma can be parallel to those of other conditions, it is essential to see a doctor if any of these symptoms persist, especially if there is a known history of asbestos exposure.


Mesothelioma, though rare, is a severe and aggressive form of cancer, mostly associated with asbestos exposure. A thorough understanding of the risk factors and early symptoms is crucial for early detection, which could improve the efficacy of treatment and improve survival rates. If you or a loved one have had prolonged asbestos exposure or exhibit any of the mentioned symptoms, seeking medical advice promptly is essential. Likewise, consulting with reliable lawyers to pursue a lawsuit is also advised.